Welcome to Volume 8 of the Eating Disorder Research Library. The primary goal of this newsletter is to provide professionals, patients and families with an update of the most recent research on eating disorders. Each quarterly issue will provide a listing of all indexed research that has occurred in the previous three months with a quick link to an abstract of the article or full text. Articles are grouped by subject matter to facilitate easy access. We have also created a “Spotlight” section that provides brief reviews of some articles of particular interest. We hope that providing easy access to the basic research in the field will enhance greater use of evidence based information among professionals and greater awareness of the science of the field for patients and families.
Click any of these links to jump down the page to related content:
Akman, A.O., Cak, H.T., Pehlivantur,-Kizilkan, M. Balik, Z., Akbulut, O., & Kanbur, N. (2019). Sounds unrealistic: an adolescent girl with Anorexia Nervosa consumes 19 L of fluid in a few hours: What happens to the physiology? Eating and Weight Disorders. E-publication ahead of print.
https://doi.org/10.1007/s40519-019-00777-7
Review by Elizabeth Erickson, DO
Eating disorders are not strictly disorders of food consumption, but often of abnormal drinking behaviors that vary in clinical presentation. This article is a case study that demonstrates the acuity and extreme drinking behaviors that can be present in an ED patient, and how one must be through in evaluating not just food consumption, but fluids, as well.
The case discussed was that of a 16 y.o. female with AN-R and Major Depression. Patient was admitted to inpatient level of care and started on nutritional support with a low-calorie meal plan. On the second day of treatment, patient demonstrated a 2 kg weight gain. On clinical exam, patient was disoriented and drowsy. Subsequently, patient discussed experienced a tonic-clonic seizure, and her serum sodium was found to be 116 mEq/L with a specific gravity of 1.002. Patient’s calculated serum osmolality was calculated at 239.9. Patient was diagnosed with acute hyponatremia and was started on 3% hypertonic saline solution. Only following this event, did the team discover that patient had ingested 19 L of water to expedite discharge.
Why is This Important?
Hyponatremia in ED’s is a result of a variety of factors. If the cause is unknown, urine sodium and urine specific gravity, are helpful tools in identifying a root cause. In restrictive disorders, hyponatremia might be secondary to either dehydration (restriction of fluids) or overhydration (water loading). Hyponatremia is the most common cause of overhydration, and is defined by a plasma sodium less than 135 mEq/L. Values below 125mEq/L are considered as severe hyponatremia. Initial goal in treatment is differentiation of hypotonic from nonhypotonic hyponatremia. A low serum osmolality, as noted in this case study, suggests hypotonic hyponatremia. Once diagnosis is established, volume status should be assessed. Due to the acute onset of severe symptoms in this case, immediate treatment with hypertonic saline was performed. It is essential to keep in mind that electrolyte abnormalities should be considered one of the primary considerations in a differential diagnosis for a patient with an eating disorder and new seizures.
Of note, chronic overhydration, common in ED’s, leads to downregulation of aquaporin 2 water channels, resulting in adaptation mechanism of urinary water excretion. In the case reviewed, however, the patient acutely over consumed water, in which water intoxication can occur. Water intoxication (dilutional hyponatremia) can occur at approximately 3-4 L in less than an hour, or when the consumption exceeds the capacity of water excretion, roughly 10 L a day. In this case, patient consumed 19 L of water in a short time. Any abnormal fluid intake by ED patients may result in severe, and acute medical complications.
This case demonstrates that a thorough clinical assessment of hydration and drinking behaviors is necessary during the management of ED’s, and electrolyte abnormalities should be a primary focus for a patient with an ED and new onset seizures.
Neumayr, C., Voderholzer, U., Tregarthen, J., & Schlegl, S. (2019). Improving aftercare with technology for anorexia nervosa after intensive inpatient treatment: A pilot randomized controlled trial with a therapist – guided smartphone app. International Journal of Eating Disorders, 52(10), 1191-1201.
https://doi.org/10.1002/eat.23152
Forty female patients were recruited to the study following discharge from inpatient treatment. All 40 patients had routine discharge plans. 20 of the patients were randomized to an 8 week smartphone based aftercare intervention with therapist feedback as an adjunct to their routine discharge plan (intervention group) and the other 20 continued with their routine discharge plans (control group). The intervention group was given access to a smart phone app designed specifically for patients with eating disorders (Recovery Record). The app focuses on self -monitoring, meal planning, tracking eating disorder behaviors, and includes a variety of psychological interventions taken from CBT, DBT, ACT and MET. The therapist intervention was accomplished via the app and occurred 2x per week for the first 4 weeks and 1x week for the second 4 weeks. The therapists were eating disorder specialists and their feedback, delivered through the app, was focused on eating behaviors, mood regulation and overall motivation. Results showed a high level of adherence and a very high acceptance of the app and the aftercare intervention by patients. End of intervention results (8 weeks), indicated a small to moderate effect size advantage in overall improvement favoring the app assisted intervention group vs. the control group. At six month follow-up the advantages of the Intervention group had eroded and there were no significant differences between the groups.
Why is this important?
Relapse rates are high for patients with AN that receive inpatient/residential treatment. Current research indicates that between 20 to 40% will relapse shortly after discharge. One notable factor that seems to contribute to relapse is when patients return to geographic areas that do not have access to specialized eating disorder providers. Technology based interventions, particularly an eating disorder specific app such as Recovery Record, that allows for real time monitoring of moods, thoughts, and behaviors known to predict relapse, coupled with ongoing feedback from a remote eating disorder specialist could greatly reduce relapse rates. In the current pilot study, despite small sample sizes, the app/ed specialist therapist intervention group showed better overall improvement until the intervention was stopped. Also noteworthy, most patients reported that the feedback from the ED expert was the most helpful feature in the app and 2/3 of the patients reported that they were not sure that they would keep using the app without the weekly therapeutic feedback and guidance. Clearly this finding sets the stage for a study comparing therapist assisted app vs app alone. Although the current study suffers from all of the limitations of small preliminary study, it shines a light on the very exciting field of technology- based interventions that potentially, allow us to extend the reach of specialized care to areas that lack such resources.
Avila, J. T., Golden, N. H., & Aye, T. (2019). Eating disorder screening in transgender youth. Journal of Adolescent Health, 65(6), 815–817.
https://doi.org/10.1016/j.jadohealth.2019.06.011
Review by Megan Riddle, MD PhD
Avila's article, Eating Disorder Screening in Transgender Youth, adds to the nascent field of research regarding eating disordered behaviors in individuals who are transgender or gender non-binary (referred to collectively as transgender in this review). A search of Pubmed for "eating disorder*" and "transgender" reveals a mere 41 articles, 40 of these published since 2011. This speaks to both our relatively limited knowledge base and our need to increase awareness in this area.
This article describes survey results from patients ages 13 to 22 at an academic multidisciplinary gender clinic. Subjects completed the EDE-Q as well as two additional questions assessing the role of weight manipulation for gender-affirming purposes. In addition, the researchers tracked BMI, calculated based on sex assigned at birth, and whether an individual was taking gender-affirming hormones. A total of 106 individuals completed the survey, 61% identifying as transmasculine, 28% as transfeminine and 11% as nonbinary. On average EDE-Q values were within population norms, while 15% had elevated global scores. A total of 63% of all subjects reported intentional weight manipulation for reasons of gender identity. Interestingly, they did not find a correlation between intentional weight manipulation and elevated EDE-Q scores. Also, no significant difference was observed in individuals with elevated EDE-Q scores with regards to gender identity or use of gender-affirming hormones.
Why is this important?
Avila’s work is consistent with existing literature indicating that transgender individuals are at increased risk of developing eating disorders, even when compared to the group typically considered at highest risk, cisgender heterosexual women. A survey of nearly 300,000 US college students found rates of eating disorders in transgender students to be 15.8%, significantly higher than the 1.85% of cisgender heterosexual women reported an eating disorder diagnosis. In this study, transgender individuals were also at increased risk relative to cisgender heterosexual women with regards to diet pill use (13.5% vs. 4.29%) and vomiting or laxative use (15.1% vs. 3.71%) in the past month. Furthermore, research indicates that transgender individuals with eating disorders are at higher risk than their cisgender counterparts with eating disorders (or transgender individuals without eating disorders) for nonsuicidal self-injury, suicidal ideation, and suicide attempts.
McBride, C., Costello, N., Ambwani, S., Wilhite, B., & Austin, S. B. (2019). Digital manipulation of images of models' appearance in advertising: strategies for action through law and corporate social responsibility incentives to protect public health. American Journal of Law & Medicine, 45(1), 7-31.
Review by Millie Plotkin, MLS
As digital manipulation of photographs in advertising has become a standard part of marketing practices, there are concerns about how these unrealistic images contribute to body dissatisfaction.
There have been several studies on the labeling photographs with disclaimers stating they have been retouched (see review by Plotkin in vol. 6 of the Eating Disorder Research Library). This article summarizes that research, but then makes a bold new suggestion of how to incentivize companies to stop digital manipulation of human models.
Several countries have created Advertising Standards Authorities (ASA) which regulate advertising across all forms of media. Theses ASAs write advertising codes which ban offensive and misleading images, as well as responding to consumer complaints. However, in the United States the First Amendment right to free speech has been seen as a barrier to laws that restrict advertising methods. Self-regulation in the American advertising industry does exist and several large national companies such as the pharmacy chain CVS and clothing retailer Target have committed themselves to using non-airbrushed images in their stores. However, participation is entirely voluntary and has yet to be adopted on a large scale. Regulation by the Federal Trade Commission has been suggested in the past, but the 2016 Truth in Advertising Act stalled in committee and has not been reintroduced. The authors of this article suggest that a voluntary certification program would be another way of encouraging participation in manipulation-free advertising.
This article discusses the use of tax incentives for companies to comply with the voluntary advertising standards. One method would be to create a tax that is in essence a fine for manipulating the weight, age, or skin color of models. Companies might be able to use the First Amendment to fight this tax, but it has yet to be tested in court. Alternatively, tax deductions could be created for the hiring of models and creation of photo layouts, as long as there is no digital manipulation involved in the advertising campaign. Both of these methods could be difficult to enforce because marketing is such a large industry, and could end up being burdensome to the Internal Revenue Service, which oversees taxation.
Why is this important?
There is a large body of research on the negative influence on print media on body image. Over the last several years, public health experts have been seeking ways to reduce digitally-manipulated images within advertising in hopes of moderate the impact on consumers. The tax incentives suggested in this article are a new tactic which has not previously been explored.
In June 2019, a bill was introduced in the Massachusetts legislature to create a tax credit as incentive for unaltered advertisements. This bill would allow for a 1% credit, up to $10k, every year for personal care, cosmetics, and apparel businesses. In order to qualify, a business would need to provide proof that they are complying with criteria created by the state Department of Revenue in consultation with the Department of Public Health. If this credit is successful, it could form a model for other states and perhaps even federal legislation.
Alanon Pardo, M. D. M., Ferrit Martin, M., Calleja Hernandez, M. A., & Morillas Marquez, F. (2019). Adherence of nutritional support prescriptions to clinical practice guidelines in patients with anorexia nervosa. Nutrición Hospitalaria, 36(5), 1001-1010.
https://doi.org/10.20960/nh.02223
Anderson, L. M., Smith, K. E., Nuñez, M. C., & Farrell, N. R. (2019). Family accommodation in eating disorders: a preliminary examination of correlates with familial burden and cognitive-behavioral treatment outcome. Eating Disorders. E-publication ahead of print.
https://doi.org/10.1080/10640266.2019.1652473
Barakat, S., Maguire, S., Smith, K. E., Mason, T. B., Crosby, R. D., & Touyz, S. (2019). Evaluating the role of digital intervention design in treatment outcomes and adherence to eTherapy programs for eating disorders: a systematic review and meta‐analysis. International Journal of Eating Disorders, 52(10), 1077-1094.
https://doi.org/10.1002/eat.23131
Bardone‐Cone, A. M., Alvarez, A., Gorlick, J., Koller, K. A., Thompson, K. A., & Miller, A. J. (2019). Longitudinal follow‐up of a comprehensive operationalization of eating disorder recovery: concurrent and predictive validity. International Journal of Eating Disorders, 52(9), 1052-1057.
https://doi.org/10.1002/eat.23128
Bardone‐Cone, A. M., Johnson, S., Raney, T. J., Zucker, N., Watson, H. J., & Bulik, C. M. (2019). Eating disorder recovery in men: a pilot study. International Journal of Eating Disorders, 52(12), 1370-1379.
https://doi.org/10.1002/eat.23153
Chatoor, I., Webb, L. E., & Kerzner, B. (2019). Anorexia nervosa and depression in a 5‐year‐old girl: treatment with focused family play therapy and medication. International Journal of Eating Disorders, 52(9), 1065-1069.
https://doi.org/10.1002/eat.23129
Cloutier-Bergeron, A., Provencher, V., Mongeau, L., Paquette, M.-C., Carbonneau, E., Turcotte, M., & Begin, C. (2019). Does HealthAtEvery Size(R) fit all? A group-based trajectory modeling of a non-diet intervention. Appetite, 143, 104403.
https://doi.org/10.1016/j.appet.2019.104403
Coffino, J. A., Udo, T., & Grilo, C. M. (2019). Rates of help-seeking in US adults with lifetime DSM-5 eating disorders: prevalence across diagnoses and differences by sex and ethnicity/race. Mayo Clinic Proceedings, 94(8), 1415-1426.
https://doi.org/10.1016/j.mayocp.2019.02.030
Conti, J., Calder, J., Cibralic, S., Rhodes, P., Meade, T., & Hewson, D. (2017). ‘Somebody else's roadmap’: lived experience of Maudsley and family-based therapy for adolescent anorexia nervosa. Australian and New Zealand Journal of Family Therapy, 38(3), 405-429.
https://doi.org/10.1002/anzf.1229
Davis, L. & Attia, E. (2019). Recent advances in therapies for eating disorders. F1000 Research, 8.
https://doi.org/10.12688/f1000research.19847.1
Demmler, J. C., Brophy, S. T., Marchant, A., John, A., & Tan, J. (2019). Shining the light on eating disorders, incidence, prognosis and profiling of patients in primary and secondary care: national data linkage study. British Journal of Psychiatry. E-publication ahead of print.
https://doi.org/10.1192/bjp.2019.153
Dimitropoulos, G., Lock, J. D., Agras, W. S., Brandt, H., Halmi, K. A., Jo, B., ... & Woodside, D. B. (2020). Therapist adherence to family‐based treatment for adolescents with anorexia nervosa: A multi‐site exploratory study. European Eating Disorders Review, 28(1), 55-65.
https://doi.org/10.1002/erv.2695
Frayn, M., Khanyari, S., & Knäuper, B. (2019). A 1-day acceptance and commitment therapy workshop leads to reductions in emotional eating in adults. Eating and Weight Disorders. E-publication ahead of print.
https://doi.org/10.1007/s40519-019-00778-6
Gorwood, P., Duriez, P., Lengvenyte, A., Guillaume, S., & Criquillion, S. (2019). Clinical insight in anorexia nervosa: associated and predictive factors. Psychiatry Research, 281, 112561.
https://doi.org/10.1016/j.psychres.2019.112561
Graham, A. K., Wildes, J. E., Reddy, M., Munson, S. A., Barr Taylor, C., & Mohr, D. C. (2019). User‐centered design for technology‐enabled services for eating disorders. International Journal of Eating Disorders, 52(10), 1095-1107.
https://doi.org/10.1002/eat.23130
Hamadi, L., & Holliday, J. Moderators and mediators of outcome in treatments for anorexia nervosa and bulimia nervosa in adolescents: A systematic review of randomized controlled trials. International Journal of Eating Disorders. E-publication ahead of print.
https://doi.org/10.1002/eat.23159
Herpertz-Dahlmann, B. & Dahmen, B. (2019). Children in need-diagnostics, epidemiology, treatment and outcome of early onset anorexia nervosa. Nutrients, 11(8), 1932.
https://doi.org/10.3390/nu11081932
Jennings, K. M., Bodell, L. P., Crosby, R. D., Haynos, A. F., & Wildes, J. E. (2019). Mixture modeling to characterize anorexia nervosa: integrating personality and eating disorder psychopathology. Journal of the American Psychiatric Nurses Association. E-publication ahead of print.
https://doi.org/10.1177/1078390319862029
Jassova, K., Albrecht, J., Ceresnakova, S., Papezova, H., & Anders, M. (2019). Repetitive transcranial magnetic stimulation significantly influences the eating behavior in depressive patients. Neuropsychiatric Disease and Treatment, 15, 2579-2586.
https://doi.org/10.2147/NDT.S203486
Johns, G., Taylor, B., John, A., & Tan, J. (2019). Current eating disorder healthcare services - the perspectives and experiences of individuals with eating disorders, their families and health professionals: systematic review and thematic synthesis. BJPsych Open, 5(4), e59.
https://doi.org/10.1192/bjo.2019.48
Jordan, J., McIntosh, V. V. W., & Bulik, C. M. (2019). Specialist Supportive Clinical Management for anorexia nervosa: what it is (and what it is not). Australasian Psychiatry. E-publication ahead of print.
https://doi.org/10.1177/1039856219875024
Kalaria, S. N., McElroy, S. L., Gobburu, J., & Gopalakrishnan, M. (2019). An innovative disease-drug-trial framework to guide binge eating disorder drug development: a case study for topiramate. Clinical and Translational Science. E-publication ahead of print.
https://doi.org/10.1111/cts.12682
Kinnaird, E., Norton, C., Pimblett, C., Stewart, C., & Tchanturia, K. (2019). “There’s nothing there for guys”. Do men with eating disorders want treatment adaptations? A qualitative study. Eating and Weight Disorders, 24(5), 845-852.
https://doi.org/10.1007/s40519-019-00770-0
Le Grange, D., Huryk, K. M., Murray, S. B., Hughes, E. K., Sawyer, S. M., & Loeb, K. L. Variability in remission in family therapy for anorexia nervosa. International Journal of Eating Disorders, 52(9), 996-1003.
https://doi.org/10.1002/eat.23138
Levinson, C. A., Christian, C., & Vanzhula, I. A. (2019). Manipulating the theoretical framing of exposure therapy for eating disorders impacts clinicians’ treatment preferences. Eating and Weight Disorders. E-publication ahead of print.
https://doi.org/10.1007/s40519-019-00751-3
Lydecker, J. A., Gueorguieva, R., Masheb, R., White, M. A., & Grilo, C. M. (2019). Examining race as a predictor and moderator of treatment outcomes for binge-eating disorder: analysis of aggregated randomized controlled trials. International Journal of Eating Disorders. E-publication ahead of print.
https://doi.org/10.1002/eat.23167
Machado, P. P. P. & Rodrigues, T. (2019). Treatment delivery strategies for eating disorders. Current Opinion in Psychiatry, 32(6), 498–503.
https://doi.org/10.1097/YCO.0000000000000542
Manuelli, M., Franzini, A., Galentino, R., Bidone, R., Dell’Osso, B., Porta, M., ... & Cena, H. (2019). Changes in eating behavior after deep brain stimulation for anorexia nervosa. A case study. Eating and Weight Disorders. E-publication ahead of print.
https://doi.org/10.1007/s40519-019-00742-4
Matthews, K., Gordon, L., van Beusekom, J., Sheffield, J., & Patterson, S. (2019). A day treatment program for adults with eating disorders: staff and patient experiences in implementation. Journal of Eating Disorders, 7, 21.
https://doi.org/10.1186/s40337-019-0252-4
McLean, S. A., Caldwell, B., & Roberton, M. (2019). Reach Out and Recover: Intentions to seek treatment in individuals using online support for eating disorders. International Journal of Eating Disorders, 52(10), 1137-1149.
https://doi.org/10.1002/eat.23133
Neumayr, C., Voderholzer, U., Tregarthen, J., & Schlegl, S. (2019). Improving aftercare with technology for anorexia nervosa after intensive inpatient treatment: A pilot randomized controlled trial with a therapist‐guided smartphone app. International Journal of Eating Disorders, 52(10), 1191-1201.
https://doi.org/10.1002/eat.23152
Paquin Hodge, C., Gauvin, L., St‐Hilaire, A., Israel, M., Azzi, M., Kahan, E., ... & Steiger, H. A naturalistic comparison of two inpatient treatment protocols for adults with anorexia nervosa: Does reducing duration of treatment and external controls compromise outcome?. International Journal of Eating Disorders, 52(9), 1015-1023.
https://doi.org/10.1002/eat.23150
Patmore, J. M., Meddaoui, B., & Feldman, H. (2019). Cultural considerations for treating Hispanic patients with eating disorders: a case study illustrating the effectiveness of CBT in reducing bulimia nervosa symptoms in a Latina patient. Journal of Clinical Psychology, 75(11), 2006-2021.
https://doi.org/10.1002/jclp.22860
Perry, M., Watson, L., Hayden, L., & Inwards-Breland, D. (2019). Using body neutrality to inform eating disorder management in a gender diverse world. Lancet. Child & Adolescent Health, 3(9), 597-598.
https://doi.org/10.1016/S2352-4642(19)30237-8
Phillipou, A., Kirkovski, M., Castle, D. J., Gurvich, C., Abel, L. A., Miles, S., & Rossell, S. L. (2019). High‐definition transcranial direct current stimulation in anorexia nervosa: A pilot study. International Journal of Eating Disorders, 52(11), 1274-1280.
https://doi.org/10.1002/eat.23146
Piers, A. D., Espel‐Huynh, H. M., & Lowe, M. R. (2019). The independent and interacting effects of weight suppression and admission body mass index on treatment weight change in patients with anorexia nervosa or bulimia nervosa. International Journal of Eating Disorders, 52(11), 1301-1309.
https://doi.org/10.1002/eat.23149
Rienecke, R., Drayton, A., Richmond, R., & Mammel, K. A. (2019). Adapting treatment in an eating disorder program to meet the needs of patients with ARFID: three case reports. Clinical Child Psychology and Psychiatry. E-publication ahead of print.
https://doi.org/10.1177/1359104519864129
Rohrbach, P. J., Dingemans, A. E., Spinhoven, P., Van den Akker-van Marle, M. E., Van Ginkel, J. R., Fokkema, M., . . . Van Furth, E. F. (2019). A randomized controlled trial of an Internet-based intervention for eating disorders and the added value of expert-patient support: study protocol. Trials, 20(1), 509.
https://doi.org/10.1186/s13063-019-3574-2
Sanzari, C. M. & Liu, R. T. (2019). Temporal trends in treatment utilization for disordered eating in U.S. adolescents from 2004 through 2017: a nationally representative study. Journal of Adolescent Health, 65(4), 564–566.
https://doi.org/10.1016/j.jadohealth.2019.05.005
Smith, K. A., Dandil, Y., Baillie, C., & Tchanturia, K. (2019). Well-being workshops in eating disorder wards and their perceived benefits to patients and the multi-disciplinary team: a pilot study. Brain Sciences, 9(10), 247.
https://doi.org/10.3390/brainsci9100247
Sproch, L. E., Anderson, K. P., Sherman, M. F., Crawford, S. F., & Brandt, H. A. (2019). A randomized controlled trial of group cognitive remediation therapy for anorexia nervosa: Effects on set‐shifting tasks for inpatient adults and adolescents. International Journal of Eating Disorders, 52(9), 1004-1014.
https://doi.org/10.1002/eat.23143
Stancil, S. L., Adelman, W. P., Dietz, A., & Abdel-Rahman, S. (2019). Naltrexone reduces binge eating and purging in adolescents in an eating disorder program. Journal of Child and Adolescent Psychopharmacology, 29(9).
https://doi.org/10.1089/cap.2019.0056
Strobel, C., Quadflieg, N., Naab, S., Voderholzer, U., & Fichter, M. M. (2019). Long‐term outcomes in treated males with anorexia nervosa and bulimia nervosa—A prospective, gender‐matched study. International Journal of Eating Disorders, 52(12), 1353-1364.
https://doi.org/10.1002/eat.23151
Taylor, C. B., Graham, A. K., Fitzsimmons‐Craft, E. E., Sadeh‐Sharvit, S., Balantekin, K. N., Flatt, R. E., ... & Firebaugh, M. L. Optimizing eating disorder treatment outcomes for individuals identified via screening: An idea worth researching. International Journal of Eating Disorders, 52(11), 1224-1228.
https://doi.org/10.1002/eat.23169
Wade, T. D., & Lock, J. (2019). Developing consensus on the definition of remission and recovery for research. International Journal of Eating Disorders. E-publication ahead of print.
https://doi.org/10.1002/eat.23165
Wright, C., & Waller, G. (2019). The impact of teaching clinicians about implementing exposure therapy with patients with eating disorders: A nonrandomized controlled study. International Journal of Eating Disorders. E-publication ahead of print.
https://doi.org/10.1002/eat.23171
Yim, S. H., & Schmidt, U. (2019). Experiences of computer‐based and conventional self‐help interventions for eating disorders: A systematic review and meta‐synthesis of qualitative research. International Journal of Eating Disorders, 52(10), 1108-1124.
https://doi.org/10.1002/eat.23142
Akman, A. O., Cak, H. T., Pehlivantürk-Kızılkan, M., Balik, Z., Akbulut, O., & Kanbur, N. (2019). Sounds unrealistic: an adolescent girl with anorexia nervosa consumes 19 L of fluid in a few hours: what happens to the physiology?. Eating and Weight Disorders. E-publication ahead of print.
https://doi.org/10.1007/s40519-019-00777-7
Beykloo, M. Y., Nicholls, D. E., Simic, M., Brauer, R., Mills, E., & Wong, I. C. K. (2019). Survey on self-reported psychotropic drug prescribing practices of eating disorder psychiatrists for the treatment of young people with anorexia nervosa. BMJ Open, 9(9), e031707.
https://doi.org/10.1136/bmjopen-2019-031707
Chiba, F. Y., Sumida, D. H., Moimaz, S. A. S., Neto, A. H. C., Nakamune, A. C. M. S., Garbin, A. J. I., & Garbin, C. A. S. (2019). Periodontal condition, changes in salivary biochemical parameters, and oral health-related quality of life in patients with anorexia and bulimia nervosa. Journal of Periodontology, 92(12), 1423-1430.
https://doi.org/10.1002/JPER.19-0053
Collu, R., Scherma, M., Piscitelli, F., Giunti, E., Satta, V., Castelli, M. P., ... & Fadda, P. (2019). Impaired brain endocannabinoid tone in the activity‐based model of anorexia nervosa. International Journal of Eating Disorders, 52(11), 1251-1262.
https://doi.org/10.1002/eat.23157
Dooley-Hash, S., Adams, M., Walton, M. A., Blow, F. C., & Cunningham, R. M. (2019). The prevalence and correlates of eating disorders in adult emergency department patients. International Journal of Eating Disorders, 52(11), 1281-1290.
https://doi.org/10.1002/eat.23140
Caso, J. R., Graell, M., Navalon, A., MacDowell, K. S., Gutierrez, S., Soto, M., . . . Marsa, M. D. (2020). Dysfunction of inflammatory pathways in adolescent female patients with anorexia nervosa. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 96, 109727.
https://doi.org/10.1016/j.pnpbp.2019.109727
Frank, G. K. W. (2019). Neuroimaging and eating disorders. Current Opinion in Psychiatry, 32(6), 478–483.
https://doi.org/10.1097/YCO.0000000000000544
Griffiths, K. R., Yang, J., Touyz, S. W., Hay, P. J., Clarke, S. D., Korgaonkar, M. S., . . . Kohn, M. (2019). Understanding the neural mechanisms of lisdexamfetamine dimesylate (LDX) pharmacotherapy in Binge Eating Disorder (BED): a study protocol. Journal of Eating Disorders, 7, 23.
https://doi.org/10.1186/s40337-019-0253-3
Hübel, C., Yilmaz, Z., Schaumberg, K. E., Breithaupt, L., Hunjan, A., Horne, E., ... & Breen, G. (2019). Body composition in anorexia nervosa: Meta‐analysis and meta‐regression of cross‐sectional and longitudinal studies. International Journal of Eating Disorders, 52(11), 1205-1223.
https://doi.org/10.1002/eat.23158
Janzen, M., Cheung, C. C., Steinberg, C., Lam, P.-Y., & Krahn, A. D. (2019). Changes on the electrocardiogram in anorexia nervosa: a case control study. Journal of Electrocardiology, 56, 64-69.
https://doi.org/10.1016/j.jelectrocard.2019.07.006
Mehler, P. S. (2019). Clinical guidance on osteoporosis and eating disorders: the NEDA continuing education series. Eating Disorders, 27(5), 471-481.
https://doi.org/10.1080/10640266.2019.1642031
Meneguzzo, P., Collantoni, E., Solmi, M., Tenconi, E., & Favaro, A. (2019). Anorexia nervosa and diffusion weighted imaging: An open methodological question raised by a systematic review and a fractional anisotropy anatomical likelihood estimation meta‐analysis. International Journal of Eating Disorders, 52(11), 1237-1250.
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